There are three fermented soy beverages in the US market namely, EcoNugenics, Soy Unique and Haelan. Of the three a market report analysis by Iowa State University, the last of which was done on May 2000, showed that the soy isoflavones, daidzin and genistin as well as the fermented soy isoflavone metabolites were significantly higher in the Haelan samples as compared to the other two products. For this reason we decided to use Haelan951 in the present hepatocellular carcinoma study.
The dietary nutraceutical, Haelan951, which is the subject of this application is a fermented soy supplement made by Haelan951 Products Inc. based in Seattle, Washington. Haelan 851 was approved by FDA as a beverage in the complete food category since 1985. Manufacturing, which includes plant cultivation and processing of the soybeans is done in the People’s Republic of China.
